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History of Transfer Factors research


In 1949, Dr. H. Sherwood Lawrence made a revolutionary discovery while studying tuberculosis. He determined that an immune response could be transferred from a donor to a recipient by injecting an extract of white blood cells (leukocytes) from a previously infected, now healthy, subject into a newly infected patient. He found that this extract contained a factor capable of transferring immunity. He named the substance "transfer factor."


While Dr. Lawrence’s colleagues recognized the importance of his discovery, media and medical establishment did not report about that. The failure of transfer factor to reach the marketplace might be explained by a single word: penicillin. Dr. Lawrence's discovery from 1949 came in the midst of the discovery and use of antibiotics.

In 1950, only a few months after Dr. Sherwood’s discovery, antibiotics were introduced and pharmacology gained new prominence as the frontline for battling disease. Thatstory triumphed in both the popular media and the scientific communities, virtually burying the landmark Dr. Lawrence’s findings.


Yet transfer factors have been used throughout the antibiotic age in different regions of the world such as China, Poland, Italy and others, but never have been available commercially due to the lack of technology. While consumers have not had access to information or products based on transfer factor science, researchers have continued to test and explore Lawrence’s discovery.

In the fifty years since Lawrence's pioneering work, an estimated $40,000,000 has been spent on research resulting in over 3,000 published scientific papers documenting the benefits of transfer factors. The world's leading scientists and physicians have established the safety and remarkable immune system benefits of transfer factors.

4Life Research, the supplement manufacturer, leaded by the founder and CEO, David Lisonbee, participates in this ongoing scientific research since 1997. The result of that work are several patents held by 4Life Research that allows for large-scale, commercial extraction and stabilization of transfer factors derived from bovine's colostrum and egg's yolk.